I have had a problem with every single drive enclosure I have ever bought from OWC. For some dumb reason their chipsets are not mac compatible. Go figure. The products I have bought have been Newer Technology products though so maybe they just suck but OWC needs some of that hate because they keep selling them.
I have never had a problem with various OWC enclosures until USB 3.0 became available on Macs. And OWC enclosures and OS X aren't the only enclosures/operating system having problems with USB 3.0. If you do a quick Startpage search you will turn up lots of hits about USB 3.0 problems with Windows computers...