Dropbox???? Are you using Netscape as your browser? (a kind and humorous jab)
I stopped using Wacom after upgrading to Big Sur. Could not get it installed and running. I spent a good amount of time on the phone with Wacom tech support while they guided me through multiple restarts, long in and outs, and deactivating security settings. Their actual words, "We wouldn't have this problem if Apple stopped updating their security." I realize there's several users who have not run into this problem. I'll wait.