Interesting post - there are some good ideas in here. I am going to try and get a Calgigit which will free up a pci-e slot for another SSD. I currently have a sata card in one slot and a USB 3 card in another.
Thank you for your kind remark.
To not wasting a PCIe slot for both an USB 3.0 AND eSATA card, I indeed choose for the Caldigit. Since I've installed it I have had ZERO issues with it. Highly recommended.
NOTE: Some of us have the previous Caldigit FASTA-6GU3-Pro USB3 and eSATA3 Card. So please check the website to be sure the new pro version has the same specs for booting from eSATA and or your needs-and-liking.
Cheers