So you're talking worst case (for the SSD's benefit - Sequential data) about 10x improvement with a PCIe SSD, and best case (in terms of improvement) 50x plus.
It's not even close.
Cool. I'll go ahead and grant you your figures.
SSDs really are a game changer.
For certain games, sure. But not everybody is playing the same game. Your examples:
They make things like sleep painless - close lid and the machine hibernates (and wakes) pretty instantly.
Is sleep really painful with an HD? (Actually, I wouldn't know -- I leave all my machines on 24/7, as most of them are usually doing server duties of one sort or another.)
Is app opening time really that painful? (Again, I rarely open apps; the ones I use most frequently I open when the machine turns on, and I leave them open. And since I only turn my machines on about every 2-3 months on average, that doesn't happen a lot...)
Data is written to disk instantly.
All modern operating systems cache writes, so all interaction with long-term storage takes place in the background (again, assuming you've provided your computer sufficient RAM). So again, I don't find this painful; unless your work is truly IO-bound, I don't think you often find yourself twiddling your fingers and waiting for writes to the disk. (But I guess I don't often deal with massive amounts of data, outside of some media files and a few games.)
Unless your data set fits entirely in RAM (and if you're dealing with HD or 4k video for example, it won't) the spinning disk in your machine is a massive bottleneck.
Ok, here's where my world really does conflict with yours; I've always been able to get my working data to fit entirely within available RAM (although, I have needed to increase the RAM on my computers at times). I'm not working with 4k video. I honestly don't know anybody who actually works with raw 4k video, and very few with any data that comes close to that sort of size. Most folks I know are using their machines for word processing, or spreadsheets, or just email and web needs. Even the highest-end games load themselves entirely into RAM, if you've got a decent gaming rig.
Of course, my previous job was at a database company, so I can't say that I don't know anybody who is working with large data.

(But none of their databases are small enough to actually fit onto a single SSD.)
I will agree that for some folks, SSDs really are life-changing. But not everybody spends all their time interacting with their long-term storage device.
And even if your data set DOES fit in ram, you still need to get it into RAM in the first place and commit the results when done.
Very true. But, as I've noted above, that doesn't necessarily happen very often. I'll generally load my data at the start of a work session, and work on it for several hours at a time before saving and closing it. (Interim results will indeed get stored, but as that happens in the background, I'm generally unaware of how long it takes.) In short, while the SSD would provide a boost, given my work habits, it isn't a boost I would notice as much as you do.
tl;dr: Yay, SSDs are great! But for some (most?) folks, they aren't a life-changing event; they're just another tool in the toolbox, to be used or not used in the appropriate circumstances.