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Has anyone partitioned a large drive to run Time Machine and manual backup on the same physical drive?.
I would hope not to many people do this. It's pointless. Let Time Machine have the entire drive.
There are some rules and if your backup system follows them you are pretty much safe.
1) The data should always exist on at least three different phyasical media and
2) The data should always exist in at least two different geographic locations.
"Always means even while the backup is copied or transported. Some backup programs wipe the disk clean before they start. Be rotation system will have two disks in the sam e place. So because of these types of things the "always" requirement might mean you need four different physical media
Always think of the "threats" what is it you are protecting from. Common causes of data loss are (1) Theft of equipment, (2) fire or flood, (3) operators error (4) Software bug causes coruption of data, (5) disk failure,....
A very simple system is to have three 1TB drives and use each one with Time Machne. You rotate them so that one in connected to the computer and updates automatically, one is in a fire safe in a differnt room and one is at the office. Every week or two you rotate them. Time Machine will take a few hours to update the drive