Don't know how you guys do it. My boot drive material is about 1/2 Gig. Movies, photos, TV, etc are all on other internal drives but OSX + iTunes + iPhoto + A3 backup libraries pushed past 500MB a while ago. That keeps SSDs out of my range for a couple of years or so I guess.
I can't speak to iPhoto and A3 as I don't use them, but with iTunes you can easily relocate off of the boot partition. It is just a menu option in advanced settings. It will still keep the index files on the SSD but move all the media off to another drive. My iTunes media files are almost 1 Terabyte and my index files in my user directory are just a bit over 250MB's.
I wouldn't recommend it, but you can use symbolic links to move the index files off the SSD as well. In fact, with symbolic links you can move just about anything anywhere in OS X.
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