I want to know too if it will work with COD4 on a Mac with xbox 360 controller (wired). I don't care much about being wireless, but I absolutely refuse to play Call Of Duty without the 360 controller.
Unlike most of you, I didn't grow up with diablo and unreal tournament so I could care less if the keyboard and mouse are "better." I just want to replicate the 360 experience on my mac since I don't have an xbox 360. At any rate, the game is still new for the mac so I would think 360 controller support will come officially sooner than later.