I am newbie but successfully did 2 GPU upgrades with NVIDIA Quadro (see signature). I am building a third machine for my friend (21.5, Imac 12,1) and I am thinking about swapping out the K2100M from my Imac 11,3 (27 mid 2010) and to install it on the new 21.5 Imac 12,1 (all running MACOS 12.1 stable). Instead, I am planning to order a new WX4130 for my Imac 11,3 (27 mid 2010). So far I have read many posts several times here in the forum about the AMD WX4100 cards. Currently it looks for me pretty "straight forward", similar to my K2100M experience (flashing the vBios with GOP vBios from this post)- except the need of adding the 15x15x1 mm copper plate for cooling purposes (special install) . I am not experienced enough to do any soldering etc...I would really avoid that. Can you please let me know, if you see any issues with this project and combination of GPU/iMac which I need to consider?