Interesting that this is such a wide spread issue, yet not a word from Apple. This problem started suddenly on my 1st gen 9.7 ipad pro, which has worked flawlessly up to this point. Most annoying was the virtual keyboard, my typed words constantly missing letters due to unresponsive moments. After some thought, I realised this issue arose around the same time I installed a particular game, for which the unresponsiveness was most noticable. I deleted the game, hard reset the device, and my ipad instantly returned to a working state, with no touch issues thereafter. I have no idea why this particular game would cause such problems, but seems it did. And for the record, disabling gestures, true tone, bluetooth etc. and/or altering angle/orientation did absolutely nothing to alleviate the problem on my device.