I'm using HDMI which isn't an issue with my old AMD Radeon HD 6800
At some point when you have problems like these, it's really worth looking at the stuff we normally assume to be working.
I wanted to tell you to toggle through the inputs of your monitor, but it sounds like you're using the same cable (not switching from DP to HDMI) and same monitor input that you previously used? Then both cable and setup should be OK.
On my MSI RX 480, I can switch between DP and HDMI and both work fine. But since we're talking about an unsupported configuration, I would tests a DP cable if I were you. Just borrow from someone to test...