4K Crossfire is broken under dual dXXX cards for gaming. See the anandtech review. For the 1st time in 10 years, Hackintosh here I come!
Not sure what you mean, crossfire not working at 4k is a windows driver issue that affects all PC's, not an issue with the Mac Pro (might be fixed in the driver now, as the anandtech review is 2-3 months old by now). And as always, crossfire under OS X just doesn't exist yet
That said, I build a hackintosh with dual 280x cards. Works like a charm in both windows and OS X, although in OS X you can only use one card for gaming, but you do get the dual performance for OpenCL tasks.