Reality is, even though the card will connect and work with 2 @ 6 pins, the one that plugs into the 8 will draw 110 watts if stressed with Furmark. I have seen this using Hardware Monitor. I do not believe this is anything to worry about, Furmark being a Worst of the worst case scenario.
A GTX285 will do the same and there are no threads about them blowing anything up. GTX 570 will pull 110 watts from both connectors and those have never blown anything up either.
If either of the mentioned cards caused problems, I would know about it.
I found that running a CS6 AE Ray Tracing render used substantially less power than Furmark. Cards all stayed near spec during this. In Windows NVIDIA drivers were changed to detect Furmark and throttle cards down, I believe some 580s self immolated before this was done. They probably didn't bother writing this into Mac drivers since the gear head "wonder what she can do" mentality is rare in OSX. (And getting further snuffed out)
Also, Macs will just shut down when a 580 writes a check that the PSU can't cash. I haven't been able to get a 680 to do this.