I understand. There was no mention in the original post of hardware dongle to run his software it's just an outdated database app and most likely a 32bits. I think Crossover or just plain Wine with some tweaking would would be ok. There's even hardware acceleration for some 32bits apps on Wine https://github.com/Gcenx/DXVK-macOS and could be integrated into CrossOver.No, the drivers for the dongle and the hardware instrument they need to run.