Yeah, I feel like that’s the issue, once I hold in my hand even in the case on, it can conduct with my hands and no issues are there. Only happens when the phone is one a flat surface and is not in contact with my skin, only in that case it doesn’t react to my thumb, all other fingers are fineNo issues. Generic glass screen protector "FOVAL" brand from Amazon, Apple leather case. Tried tapping it with my thumb gently and it turns on.
This almost reminds me of the weirdness back with the original 11" iPad Pros when they didn't respond well to multi touch with a screen protector on if you weren't holding the metal side with your other hand (say if it was resting on a pillow, etc). Amazingly that got fixed in an iOS update later... made me think it was a voltage kind of quirk.