macOS 27 on M1 Max Mac Studio and I can verify that Cisco Secure Client/AnyConnect VPN works fine. Teams, Outlook, Word, Excel, Powerpoint are all fine. Bitwarden, Claude desktop app, Logi+ work fine.
I am using a mix between a Dell headset and AirPods Max and both are working fine.
The only two quirks I have is the iPhone Mirroring doesn't work and for some reason, my desktop wallpaper is only showing on my main monitor and the other two are just black screens. But I can move things to those screens and use them just fine.