Wait, you're joking...right?
You're saying that your car sees an increase in efficiency that can't be consistently measured in a laboratory because the difference is so minute, and then go on to say that your car is tuned so you don't have a choice but to use only premium? When have you ever used regular gas? Before the car was tuned specifically for the properties of premium? Tuning would make the motor more efficient for whichever type of fuel being used (duh), not just changing the fuel.
Dipping back into science, the numbers I provided were based purely on cost benefit not how motors actually respond to the change in fuel. Looking at the article, going from premium to regular fuel decreases power by 5% under constant, absolutely ideal conditions (probably at the crank, which is where manufacturers measure output. But we'll assume they mean at the wheels since that'll give us a bigger difference) and we'll assume that the decrease in power corresponds directly to the additional fuel needed to compensate for the lost power (it doesn't actually correspond, the additional fuel needed is less than the power loss as a percentage) for the sake of discussion. Given that you're "around" 22mpg on premium, switching to regular would give you 20.9mpg. And you're claiming +2mpg from that, which means you should be getting 23(+)mpg...over twice the difference that the people who design the motor say there is. And that's before considering that your car isn't being operated in anything resembling ideal conditions or the myriad of unaccounted for variables.
And what do you mean, "or car like that?" Do you hate poor people or something? I guess you could make good arguments that Corvette Z06s and Ford GT500s run pretty poorly on premium...oh wait, no. It must be so rough to have a car like that and not whatever you have.