My point in sharing my experience was to add to yours. In the long run I don't see a reason to have iCleaner/Pro installed.
If we are avoiding using it because of what we suspect it might do, then how does it benefit us?
I just removed it. I don't need to clean cache files so bad that I have to have it on my phone with the potentiality for disaster or big problems if I use it.
There's already another thread of a user who used it and can't get to safe mode.
I'm sure it will be updated, if the issue in fact ultimately does end up being attributed to it. The developer is very much on top of his game and I'm sure if there is an issue, he'll squash it -- for me at least, running it every few days or even once a week to clean up crap is good enough for me, one reboot shortly after that won't bring my world to an end, and thankfully that's the only side effect I've had of using it, again if the issues are legitimately tied to iCleaner itself and not something else.