The issue is when you want it at a comfortable angle, or you want to start writing fast. It is very inconvenient (and hard on the hinges) to have to 270 degrees the thing every time you want to write or sketch. Plus I can put an iPad or Surface Pro in a folio case and people see it as a digital notebook. They don’t mind you bringing it into places where a 2-in-1 would be much more noticeable.Well, that’s the limitation on iPad hardware… if I had Mac hardware I can go upwards of 1TB of RAM and 8TB of storage along with adding a graphics card to it.
What’s so terrible about folding the keyboard backwards and taking notes? Once you fold the keyboard backwards you have the entire screen to use a stylus to take notes or sketch.
Anyway the main reason is you don’t have a good way to do a 15-25 degree angle — like the kickstand can do.
That said, I know of artists that do use 2-in-1s fine for art, so it really is a taste/feel thing.