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Increased toolbar and row height (sidebars) are a step backwards, leaving less space for content.
As is decreased contrast and lost colour for toolbar icons.
And increased windows corner radii were uncalled for as well.
I was concerned about the increased transparency which I don't care for at all and disliked in previous versions of Mac OS. Installing the beta today, I made sure to choose "decrease transparency" as the only customisation during the install process. Happy to report that looks good enough for me.
All in all, I'll get used to it.
Can't wait to run iPad / iOS apps on the Mac (though I'm sure some developers won't offer them for "segmentation" purposes).