The monitor works well for me.
This monitor is definitely built for gaming. So, gaming is not an issue at all.
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Using browser is better than I expect because now I can open 3 Windows SBS, and focus on the centre one, with 2 assistant windows on left and right.
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But I don't know if this is good for CAD/CAM. For me, it works well for other usage including PS / Affinity Photos, FCPX, Blender, etc.
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Of course, there is NOT no down side. This monitor's resolution is low (by today's standard), or more precisely, the PPI is low. IMO, with native resolution, the text actually looks bad in macOS. I found a work around which is to enable HiDPI, therefore, the monitor's UI still display at 3840x1080, but rendering at 7680x2160. With this setting, the text look much smoother in normal viewing distance.
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Both colour accuracy and brightness is good enough for me, however it's NOT IPS (but VA) panel. For me, it's not an issue at all. This is a 1800R monitor, which means if the view point is 1800mm away from the screen, your view distance won't change across the screen. But I don't think anyone will do that, it's too far away. The manual suggested optimum distance is 45-50cm, but my personal experience feel that about 80cm is the sweet spot. For 1440P monitor, may be you really want 45-50cm, otherwise, the UI / text will me too small small to read. And this is why I give up 1440P but go for this 1080P setup. I can now sit back, relax, but still easily read everything on the monitor. (I believe Samsung is just lazy to determine the real optimum view point for this monitor. 45-50cm is very reasonable for 27" monitor, but definitely doesn't make any sense for 49" monitor. Since this CHG90 is marketing as "putting two 27" monitors together", so may be they simply copy the optimum view distance from a normal 27" monitor)
Back to colour accuracy, except the very last inch on the screen edge. 80cm view point is good enough to maintain visual colour accuracy on this VA panel. But if your setting not allow you to do that, or you often need to show your work to someone next to you. Then VA can be an issue.
In terms of compatibility. It's 100% plug and play in macOS. All my 7950, R9 380, GTX 1080Ti can drive it without any issue. Of course, of older can't, it's not possible to deliver 144Hz or HDR, but the macOS will handle that automatically.
For boot screen (from my HD7950), I MUST set the DP setting to DP 1.1. But if I want 3840x1080 @144Hz, I must set DP to DP 1.2 or higher. The monitor UI is easy to use, and I rarely need boot screen, so, not too annoying to me. But if you need boot screen, this is something you need to think about.
The only function that I can't get it work so far in macOS is NightShift (I mean even with software hack). But since this monitor has 3 profiles quick switch. So, I made one profile with warm colour as "night mode", and I can switch to this mode within 1 second. Very handy.
Compare to 34UC98, CHG90 has less pixels, much lower PPI, not IPS, no speakers. But much bigger in size, much faster respond time, higher brightness, much higher contrast, much higher refresh rate. If you don't need any bigger size monitor, but want better resolution, go for 38" 3840x1600 may be a better option for working monitor.