I don't believe inteference is the fault of the controller chip itself, but from shortcuts in pcie board layout & design, but I'm sure I'll be corrected if this isn't the case.
Do you mean PCB board? That would be the card design-PCIe board layout would be the Apple logic board of the computer. A simple mistake to make since they interact so closely. There is the PCIe portion of the PCB, which is where it rests in the logic boards PCIe slot.
However-you may create peripheral disconnects when over-demanding bandwidth from the logic boards native PCIe switch, when combined with multiple secondary's to route it via lanes 3 or 4.
Native bandwidth of 4,1/5,1:
x0/x2/x4 or SoftRAID or Hardware RAID up to x4
x4/x2/x0
x16
x16
When you have required connectivity devices-just use one of the dedicated USB 2.0 ports on the machine. Use the expensive modern upgrades ports for drive ports if you are going to use multiple switch controllers, they will periodically decided things don't need bandwidth=connectivity issues.
In slots 3 or 4 you can only fit:
1 card with dual 10 Gbps controllers
or
2 cards with single 10 Gbps controllers
or
1 card with quad 5 Gbps controllers
or
2 cards with dual 5 Gbps controllers
...any greater deviation of that bandwidth will likely lead to some disconnect, at some given point, for required connectivity devices. Even those combo's are compressing bandwidths due to the PCIe 3.0 to PCIe 2.0 conversion and headroom requirements-so I've opted for single 10 Gbps card and controller for single port use (even though its dual port) to get full peripheral bandwidth, and 5 Gbps connectivity when dual ports are used.
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