A couple of little niggles. These might have easy fixes I don't know about.
2 finger scrolling backwards in safari. Now fixed to 3 fingers thank you to a previous post.
Finder seems to keep reverting back to sort by name rather than sort by last modified which is annoying for what I do. I have to download a file frequently to upload to our webshop and have almost uploaded an old file by mistake.
Finder no longer has the info bar showing 1 item 250gb available
The new Finder side bar isn't as nice as the old one in my opinion.
Mail has a nice new look, but can it be set to split horizontally rather than vertically?
Mail's mailbox icons are too box and I have to now scroll down to view them all. My many rules for sorting are now hiding emails if the mailbox starts with the letters M and onward
Mail's unread counter in the dock is unreadable unless you have a big dock which I don't. Half my apps seems to have the new icon and half have kept the old icon. Skype has the new one and Adium old...
Chrome is easy to pop into full screen, but not as easy as safari to get out of it. had to go into the view settings to get back out of full screen. safari has the little icon in the top right.
just my 2p