With a little bit of experience, you can replace the card without fully removing the motherboard. Also you can take it out without removing the PSU. So it can be done in like 15-20 minutes if you have done it a few times already![]()
I 100% believe that to be true on a 27" iMac and I've seen YouTube videos to prove it. I cannot foresee how it can be done on a 21.5" one, but if it can, I would surely love to see the technique!