Oh please, all of you, stop with this. These apps are aimed at pros, not dabblers and hobbyists and are priced accordingly. GIMP is no match for Photoshop, CMYK is not the be-all of pro features.
We'll be buying because we have work to do. So if you're making money with this stuff, then the price is a drop in the ocean... even as a freelancer, I could pay for the Design Premium suite with the payment from just one job.
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I'm not the person to ask but isn't Pages good enough for basic layout? I've never used it. I've seen people create nice posters in PowerPoint of all things... you've got PDF creation right there in OSX.
There's also Ragtime and a number of cheaper page layout apps...
As far as vector work is concerned, then something like this? $US95
http://mac.softpedia.com/get/Graphics/EazyDraw.shtml
I've got to be honest, I think many people here think they need more than they need... what 'hobbyist' needs to work with spot colours or have access to many of the features that they don't even know exist?
If you're a genuine student, then there's substantial edu pricing. There's just too much whining from people that don't
need this stuff. Most pros aren't going to bat an eyelid; it's part and parcel of their overheads.