Yes, Boot Camp Assistant.
It should be fairly easy to install. But you need special pci-e power cables, mini-to regular 8 pin cables. Belkin or OWC.
And the card should not be to long. Max 304 mm / 12 inches (tight fit). RTX 4060 or RTX 4070 cards will have more than enough room, and no cooling proplem.
MacOS will not support the cards, of course.
I installed Windows 10 on a separate SSD HD, which does not have boot issues like the NVMe cards.
I have only MPX cards in my machines for now.
The strength of the Mac Pro is the graphic power you can get. As
avro707 expained, the CPU is old, but it also supports more RAM. 16-core up to 768GB RAM.