So, Windows 10 is being a fickle beast, but that's not surprising since the Node doesn't have the updated firmware. Currently, bootcamped Win10 doesn't detect the Node at all and after a small, recent Win10 update was applied it BSODs 90% of the time when booting regardless of whether or not the Node is plugged in. I can run my Boot Camp Win10 in Parallels without issue, so there definitely seems to be something amiss with Thunderbolt at this point.
On the flip side, I have an ASUS G750 laptop with a TB2 port running Win10 and it was plug-and-play. Install the drivers, a couple of reboots, unplug/replug the Node in the laptop, and away it went. Steam VR test maxed out and had 0% below 90fps.
I tried running the Node firmware update on the laptop and it was able to detect the Node but said that the controller didn't support firmware updates, so I'm currently stuck trying to find someone with a Win10 TB3 laptop or shipping the controller board off to AKiTiO for their free firmware update service.