You can fit four in - whether you can power them I dont know.
Probably not at the highest class card. Each MPX Bay only has two 8-pin connectors. Cards which require 8+6 or 8+8 to power up aren't going to provision out of the MPX Bay's two double wide slots. There is one more 6-pin just above MPX Bay 2 . (near slot 5).
The "max" GPU power delivery for a count of 4 GPU packages is via MPX modules. Perhaps get away with 3 cards, but four is a stretch. Just two higher end, double wide "mainstream" cards is what Apple's baseline design is for.
"...
Alternatively, each MPX bay can support:
- One full-length, double-wide x16 gen 3 slot and one full-length, double-wide x8 gen 3 slot (MPX bay 1)
- Or two full-length, double-wide x16 gen 3 slots (MPX bay 2)
- Up to 300W auxiliary power via two 8-pin connectors
..."
support.apple.com
Multiple 250W cards per bay isn't matching up with those specs. Can "hack" around it for one bay but it will be tough to repeat that hack for the second bay. You can get to higher counts if 'slim down" the GPU cards power profile wise. (e.g., e.g each take one 8-pin + bus power (+75 ) )
The high add-in card count is far more geared toward Audio/video capture andn/or storage I/O . Not GPGPU bulk nodes.
The other big leap is whether "Big Navi" is really going to be a big leap with Metal in this particular niche area ( ray tracing. ). I won't bet on that short term after those cards general release. It wouldn't be surprising that it wasn't until next WWDC (2021) to see pragmatic traction there.