I do not know if Big Sur beta 6 is compatible. If not, is it not compatible because of these new AMD cards? Or for some other reason? The T2 chip? Something else?
And, for some of us, Big Sur fixing this issue isn't necessarily an option right away. Why? Because that's a whole new operating system and many audio plugin manufacturers, for example, traditionally do not have the capacity (being smaller dev studios) to instantly update their software to work on Big Sur if things radically change. So, I, for example, typically wait quite a long time before upgrading and certainly don't do so in the middle of a project.
I know I shouldn't assume anything (making an "ass" out of "u" and "me") but I did assume that this, potentially the last Intel-powered iMac, would be compatible with the current macOS that has been out for a considerable amount of time. But then again, these cards didn't officially come out until earlier this month. So, is it an Apple fix? Is it an AMD fix? Will there be a fix for Catalina or will Big Sur be the fix? Will it just be ignored and the iMacs shipping a month from now will not have any issues? I didn't consider myself to be "an early adopter" with this iMac but I guess that's how it's turning out to be.
So, to make sure I didn't spend 5k on something that will annoy me every day, I guess the safest bet is to just return this and wait a bit longer.