One of the first things I typically do on a fresh install of OS X is reduce the desktop icon size to 36x36 and the font size to 10pt. (On the high-res, I reduced the icons as usual but left the font size at default 12pt.) I can fully understand how some folks would find the UI too small on the 1920x1200. For my tastes, it's perfect.
Where is the options for changing the desktop icon size. I missed that completely. Here is another tip, try this color calibration profile in this thread and see if you like it.
Note: the color calibration file is located in the middle of the page. It might take a while to get used to but I recommend it to anyone. If you don't like it, you could always change it back, but I like it very much. It's color accurate.