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Can someone point me to the post about AMD GPU screw incompatibility. I have a 2010 27" iMac 11,3 I'm upgrading. I have a Dell WX 4150 I am installing. Some where I Have seen a post about screw size incompatibility. Can someone let me know where that is? I'm obviously searching wrong.

Maybe you are referring to the smaller bolt holes on the X-Bracket? Read X Bracket here to press out the smaller hole inserts. I think others (in this thread somewhere) have also found the smaller bolts that works with the smaller hole inserts.

Key is to make sure the bolt head doesn't scrap / touch the logic board on install so a proper sized bevel head bolt sinking deeper into the original X Bracket beveled bolt hole is desirable.
 
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