Out of curiosity, have you tried launching your Adobe apps on this Mac from a BootCamp partition. If so, do you observe the same symptoms? This might sort out a software issue vs a hardware failure.
It's been stated several dozen times by experienced users that the 'glitch' is a Quartz rendering bug caused by the switches in the colour profiles and drivers. There aren't issues in Windows.
Apple thought they fixed it in the last update but they didn't look deep enough.
Things like this should have been expected anyway because the Polaris chip is very new and the drivers weren't completed until shortly before Sierra reached release candidate status (we were testing Polaris cards in Mac Pros during the betas). If the chip was ready before Sierra went into beta then bugs would have been fixed before release.