Yes, people with the 4,1 upgraded to 5,1 firmware have been successful. The HS 10.13 betas 5 and 6 include the 5,1 firmware for APFS support. The firmware upgrade is run manually AFTER the HS 10.13 beta 5 or 6 download by pressing the power button for a long time until the firmware update long chime sounds. The firmware then updates and then the install proceeds I think.
This is precisely what I did, however it would not apparently install the firmware. I can't see the screen since I have a RX480 installed, but each time I've done this 10.12 starts back up and the install of 10.13 never get's further...