I'm sorry to read this. I would suggest your only real option is to get an external monitor that your eyes can tolerate. Its not ideal and comes at a cost, but you cannot continue damaging your health. Your employer should fit the bill (unless your self employed) but worst come to the worst you need to do what's right for your health.
I've avoided "upgrading" to Big Sur for fear of bugs and incompatibility with the Adobe suite which are my tools for graphic work. Not reading good things about it generally.
First off— thank you for this incredibly warm and considerate reply.
I also use CC, and that works fine I've only had maybe two issues where the apps get stuck at the splash screen which I never had before.
But as a graphics professional, I'm sure you'll be annoyed by apples choice to use inconsistent padding around the window buttons and UI. It took me a while to get used to, and I'm still using the computer with hesitation because the changes in mac os 11 were so minor and nonsensical I constantly feel like there's something different but I can't tell what, so I move hesitantly.
It is a partnership that I work under so I'm going to check out the latest models because I'm out of the loop and if that doesn't suffice I'll use your suggestion and try an external monitor. It's just a little uncomfortable doing so with a big imac on the desk already.