On 2015 Macs, 4K formatted NVMe drives are also trouble-free. 512B still have kernel panics on big transfers..
On 2013-2014 Macs, same thing plus you have to disable hibernation (pmset standby 0).
It only drains the battery more on long sleeps (more than 4hours).
How big do those transfers have to be? I'm constantly moving ripped mkv's and VM images of anywhere from 2 GB to 7 GB to a simple 3 TB USB 3.0 drive and haven't seen any KPs.
I think we can all agree by now that Sintech's adapters are the ones to get, they seem to have the least amount of issues.
Still can't get any SMART-related software to recognize my 960, though.