You can. It's similar to changing the resolution on my 13" rMBP. The 'best for display' is 1280x800 HiDPI, but I can change it to 900p and 1050p HiDPI for more space.
The nMP and the Retina iMac can output 1440p HiDPI on these Dell monitors (as mentioned earlier in this thread) but I have found it impossible on my 13" rMBP. So I am waiting to hear back from 15" rMBP owners with the 750GT video card if this is possible
I'm coming from a Dell 30" 2560x1600 monitor and while the 1080p HiDPI in the P2715 is gorgeous, I lost a lot of screen real-estate and was hoping to settle with 1440p.