Unfortunately in macOS it's not possible to run binaries that perform low level I/O directly, because they will run in the "user space" and not the "kernel space". The only way to run code in "kernel space" is in kexts.
But you can reload the kext by running the following commands on the terminal:
Mate that is awesome. the kext unload/load works and it instantly lowers the GPU to 0.
It's strange that sometimes the kext is not working on wake as the logs show that's it's running like it should:
2017-11-26 14:17:17.002457+0000 0x424dd Default 0x0 0 kernel: (AMDGPUWakeHandler) Waking up
2017-11-26 14:17:17.002459+0000 0x424dd Default 0x0 0 kernel: (AMDGPUWakeHandler) Disabling GPU