FYI, I have a Mac Pro 6 core connected to a Dell 5k monitor (two DP) and I get a flicker on the right hand side of the screen when I do any intense hard drive activity. So if I test the drive speed I get lots of flickering and at idle very little. Using a scaled screen mode gave more flickering but the default half res did not stop it completely.
I too went to Apple to complain and they did replace my graphics card but I still got the issue. I then contacted Apple Care and got the run around for several month to be told they can see something but it might be fitted in an OS update in the future and good bye. Later I did find that some beta versions of Mac OS did not flicker, so I suspect a graphics driver issue.
Since then I have replaced the CPU to a 10 core and replaced the hard drive to a Samsung NVME drive and it still flickers.
In the end I fitted an external graphics card (Radeon VII) and I now get no flicker.
Yes
When I use blackmagic egpu pro
There is no flicker