There are multiple reasons why your Mac wouldn't wake from sleep, some of which depend on how you tried to wake and some of which depend on your dGPU. If you provide info about your dGPU and the version of OCLP that you used, others here (especially those with MP5,1) may be able to help you.
Also, did you try to wake with keyboard/mouse only, or did you also try to wake by briefly pressing the power button?
I tried keyboard/mouse, then pressed the power button for a moment. Didn't wake the Mac.
However, I was also running into other problems where the Mac would boot just fine in Monterey, but not in any of my other Mac OS's, not any of the spinning drives, not the NVMe blade. I was in a world of trouble, no matter what I did, I got a black screen with a prohibited sign. Or a grey screen with a prohibited sign. For a while I had no access to the Mac at all as it also suddenly wouldn't boot into Monterey any more.
I opened up the Mac, removed all my drives but one empty, clean SSD. I was also thinking that maybe some of the problems were caused by the fact that I have a Sapphire RX 580 8GB that isn't flashed so I don't have an Apple boot picker. So I decided to swap it out for the old GT120. Then I managed to boot into the one SSD, uninstalled OpenCore.
So then I started over, installed OCLP again, but now with the GT120 and this time following the step by step guide by Mr. Macintosh on YT. So Monterey works (and wakes from sleep!). But again, the Mac did not boot into my main drive, which is an NVMe blade in a PCIe card slot running High Sierra. It does boot from a spinning drive with High Sierra. But I need my main drive. So, I thought, as OpenCore is installed on a thumbdrive and not actually on the SSD with Monterey, I could try disconnecting and removing that thumbdrive. And sure enough that worked. I don't know if this is a smart move, but it was the only thing I could think of and at least I now managed to boot into my main drive, although it took quite a bit of time for it to boot. I need Monterey only for one specific task, but my main drive will be the NVMe drive with High Sierra because it is very stable and does everything I need it to do, except for the one thing I need Monterey for.
I have not yet tried connecting the thumbdrive with OpenCore but I am assuming I can then boot into Monterey again.
I also want to take out the GT120 and put back in the RX 580, but I'm a bit afraid to do so as I will lose the native bootpicker.
Long story. Sorry. I am new to OpenCore and it can be rather daunting. Thank you for replying. Appreciate that. Although I bet you got more back than you bargained for!