Congratulations you made it!
Suggestions:
Since you need two GPUs, and I see you made a lot of modifications, you may want to solder a pair of 12V + GND from the PSU. Trust me, it's a lot easier, saving your cables and safer. I have been using this way to drive two 1080 ti (plus an extra 12V power in the optical drive space for 3rd). I haven't encounter any shot off. Strictly speaking, in fact, electronically taping is more or less for signal not for power source as much loading as two Titan X GPU (12V 30A) would draw, and I think two 280X can be just the same.
Another suggestion is that you don't have to dangling your PCIE riser like that for your PCIE drive and USB 3.0. Put your 2 gpu to slot 1, and slot 4. That's not only better looking but also be more stable. Puting GPU to slot 4 is not hard at all. Change your spinning HDDs to SSDs and take SSD's metal case off then you have all you want. Any serious bulk files save in a NAS or USB 3.0 drive. My two cents...
Thanks for the suggestions!
I'm comfortable with soldering, like working on high-voltage tube amps. But the attach points I've seen on the PSU looked small and unprotected, and the threading of the wires out of the PSU cage seemed tricky, so I opted for the tapping approach.
I moved the 2nd GPU to slot 4, and it's a much better solution -- thank you! All the PCIe cards mount securely now and are held in place by the standard two-screw bracket/bar; no more hanging cards in space or propping them up with cardboard shims. And the Amfeltec is back in x16 slot 2 for best perf, and in case I want to do RAID striping.
At first I couldn't get the double-wide GPU card to seat properly in slot 4, then I discovered there is a metal tab sticking up where slot 5 would go:
I used pliers to bend that tab up and fold it down to the left side (part of it actually came off), and that fixed it so the card would sit flat:
A full-length double-wide card in slot 4 partially obstructs drive bays 2, 3, and 4, so I moved one high-capacity HDD to bay 1, and the other to the optical bay. I moved my Windows 10 SSD from the optical bay to drive bay 2. I was able to fit the SSD in a sled adapter above the 2nd GPU in drive bay 2 -- although it appears to be pushing the GPU card down slightly. If I let the SSD hang by itself, unattached to the sled, it leaves a little more room. Side view:
Looking up into the drive bays:
Rear view, showing that all 2nd GPU ports are accessible: