History: I purchased a new mini in February. After a couple of weeks, it began crashing (and rebooting) unexpectedly with a 150 error, while I was doing stuff (not asleep, not restarting, etc). After a week of round and round with Apple (try this, wait until it crashed again, call back, catch up another support person, try this, rinse repeat), they finally told me to take it in for a motherboard replacement. That was March and the motherboard replacement happened successfully (if not painfully).
On April 21st, crash. This time it was the 210 error and actually had a stack trace (all the prior crashes had no stack trace, and very little other information in the report). Again, while I was using it (I never allow it to sleep in any event). Given that it was several weeks later, I decided to wait and see. Again last night it crashed/rebooted again while I was actively using it. Same error, though different stack trace and different low-level panic message.
At this point, I'm still up in the air about what to do. Not sure if this is 1) a hardware issue, 2) a BridgeOS error (which it seems there are conflicting reports if that can actually be updated by a macOS update), 3) something environmental, though I had exactly the same peripherals on a MacBook Pro running for years with no crashes. #1 seems less likely unless there's just some systemic issue with the T2 chip, #3 is going to be a bear to figure out since crashes are so far apart, so I'll likely hold out hope that the next update will resolve the issue (#2).
One thing is clear: quality at Apple continues on the decline. I've been a Mac user and developer for over 30 years, and even in the unstable years of System 7&8, I don't believe I've ever seen such consistent instability as we've seen over the past several years. This is exacerbated by their reticence to fix or even acknowledge issues. We have several open bugs on Radar and others which were closed as duplicates, that are years old and there's no sign that they will ever be addressed. I really hope someone at Apple is paying attention, because it feels as if quality is taking a back seat.