I'm happy to report that I have 12.0b1 running on my cMP 5,1 with OCLP 0.1.8. The OS partition is on a Samsung 860 SSD connected to a PCIe SATA 3 controller card. This is indeed a major feat, as it is widely reported on Macrumors and elsewhere that (particularly) 5,1's are not reliably able to boot beyond 11.2.3 without many hard (or eventually some, for the lucky ones) cold reboots - with, it appears, no-one yet able to do 20 consecutive reboots. [cMP 3,1, MBPros, Mac minis, iMacs seem less prone to this problem].
The only issue I can initially see is that neither of my ethernet ports are working with 12.0b1 - thankfully WiFi still does. I've read through this whole tread from page 1 but haven't yet read of a proper 'fix'. Any help would be appreciated. System Info shows that I have the following kext loaded for both ethernet addresses: /System/Library/Extensions/IONetworkingFamily.kext/Contents/PlugIns/Intel82574L.kext. Hopefully this can get fixed with either a older kext injection into OC or further patcher updates or with later betas/releases from Apple.
Update: I installed the next OCLP 0.1.9 but that refuses to load 12.0b1 for me (it’s still ok on older OS’s). The verbose screen stalled randomly at any of the early NVMe/USB/Ethernet/LocalSigningPublicKey config/load lines on multiple tries. I returned to OCLP 0.1.8 and it booted up first pop. I’ll continue to try out this patcher version and report back on its success/hang rate [...not that good actually: about 1 in 7 boots. I must have fluked the easy initial installation and the later CCC backup and test with one reboot. It's been downhill since, trying off a cloned SSD copy. I think the slower original 5400rpm HD increased the chances, but that's not an ongoing solution, is it?!]
Background: Having previously not been able to get OCLP 0.1.5 or 0.1.6 running on my Mac (seems I'm an odd one out in this regard), I tried 0.1.7 last night and, to my surprise, it did run - getting to the picker screen. However, when I used it to complete my half-finished Monterey installation, that patcher version triggered a huge amount of nvram rebuilding, with 100(0)'s of lines of code flashing by for several minutes, then ultimately stalling. That rebuilding also corrupted my ability to boot back into 11.2.3, until I cleared the nvram and went back to a Martin Lo OpenCore package. As some bug was subsequently found quickly by the OCLP developers, 0.1.8 followed a few hours later and it seems to be a significant advancement for unsupported Macs overall. Well done to the developers!