It depends on the device.What model is your MOTU interface? They usually support interfaces that are quite old. I have an Ultralite that connects with Firewire, and it still works in Sonoma.
PSA: FireWire isn’t completely dead even with macOS Sonoma by Allan Tépper - ProVideo Coalition
My Mac Mini M1 is currently running macOS 12.7.1, not the latest Sonoma 14.1.2. Many recent articles and YouTube videos had alarmed me initially, since they all state that Apple dropped support for Core Audio devices over FireWire with Ventura and Sonoma. Even though that seems to be true...
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